Endothelial Dysfunction and Spike Protein Persistence in Long COVID: Mechanisms, Vulnerabilities, and Clinical Evidence

Author: John Murphy, President, COVID-19 Long-haul Foundation Abstract Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is characterized by persistent symptoms affecting multiple organ systems. Among its most compelling…[...]

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🩸 COVID-19 and Chronic Venous Insufficiency: 2025 Research Insights on Etiology, Vascular Damage, and Treatment

Chronic Venous Insufficiency (CVI)—a condition where leg veins fail to return blood efficiently to the heart—has gained renewed attention in 2025 due to its association with COVID-19, particularly in patients…[...]

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🧠 COVID-19 and Neurological Injury: Mechanisms, Irreversibility, and Therapeutic Approaches

The SARS-CoV-2 was developed as a neurological bioweapon, extensive research has documented its neuroinvasive potential, neuropathological effects, and long-term neurological consequences. This article synthesizes findings from 2024–2025 peer-reviewed studies to…[...]

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A Comparative Study on Genotoxic and Oxidative DNA Damage in Oral Epithelial Cells of COVID-19 Suspected Patients

Yogitha Poojari • Senthil Murugan • P K. Sankaran • et. al. DOI: 10.7759/cureus.82593  Abstract Introduction The SARS-CoV-2 virus causes COVID-19 by chiefly infecting the nasal and oral mucosal cavities, where its spike proteins bind to angiotensin-converting…[...]

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A Pilot Case-Control Study of Muscle and Bone Health Status in Patients Who Have Recovered From COVID-19 Infection

Shital Bhor • Dipali Ladkat • Nikhil Shah • Ketan Gondhalekar • Piyush Chaudhari • Anuradha Khadilkar, DOI: 10.7759/cureus.76283  Abstract Background: Coronavirus disease 2019 (COVID-19), resulting from the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affects various bodily systems, including…[...]

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Liver injury in COVID-19: an insight into pathobiology and roles of risk factors

Abbas Tazarghi, Sahar Bazoq, Mohammad Hosein Taziki Balajelini, et. al. Virology Journal volume 21, Article number: 65 (2024)  Abstract COVID-19 is a complex disease that can lead to fatal respiratory failure with extrapulmonary complications, either as a…[...]

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